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Author: Admin | 2025-04-28
The treatments can produce a variable effect on sexual function ingeneral and on erectile function in particular. Generally, the different therapies for BPH can negatively affect erectile function, but improvement after tre tment has been also described. In medical therapies, the α1-adrenergic-blockers have the fewest sexual side effects, mainly retrograde ejaculation (RE), while 5α-reductase inhibitors appear to produce decreases in libido, erectile dysfunction (ED) and RE. Among surgical therapies, transurethral resection of the prostate and openprostatectomy have low rates of ED but a high incidence of RE. Compared with transurethral incision of the prostate, this procedure has fewer adverse sexual effects. Minimally invasive procedures such as laser ablation, transurethral microwave thermotherapy or transurethral needle ablation have fewer side effects than other surgical options, although their effectson erectile function have not been adequately reported.This chapter examines the diabetogenic potential of different antihypertensive drug classes. Some antihypertensive drugs aggravate glucose tolerance; betaadrenoceptor antagonists and thiazide diuretics in combination are most commonly implicated. Erectile dysfunction is a significant problem in men with hypertension, often thought to be related to their antihypertensive treatment. More recent evidence suggests that vascular abnormalities can lead to pathophysiological changes that are causative both in hypertension and erectile dysfunction, therefore leading to controversy about the relative contribution of adverse antihypertensive drug effects. The evidence relating to thiazide diuretics, centrally acting sympatholytic drugs, and beta-adrenoceptor antagonist effects on sexual function has been reviewed, with suggestions about the management of erectile dysfunction in hypertensive men. Studies also reveal that a number
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