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Author: Admin | 2025-04-28
Magic Mouthwash formulasThe term “magic mouthwash” has no single defined composition, but is a general phrase used to reference a soothing or therapeutic oral rinse of multiple ingredients. Different mixtures may be used depending on the intended effects, though a trial of a magic mouthwash is sometimes used for a broad treatment strategy without necessarily having a specific diagnosis confirmed. The following is not medical advice, but a compilation of some reported recipes. The term “stomatitis cocktail” is also used with the same meaning as “magic mouthwash.”Downsides of using magic mouthwash include potential unnecessary medication use, the cost (which may be significant given frequent need for a compounding pharmacy and multiple ingredients), as well as non-specificity of the term “magic mouthwash,” leading to potential ambiguity when communicating prior therapies to a physician. Additionally, care may be needed to avoid treating symptoms only while an underlying process progresses. Magic Mouthwash Recipe 1Rx:50 mL viscous lidocaine 2%50 mL Mylanta50 mL diphenhydramine (Benadryl) at 12.5 mg per 5 ml elixir50 mL nystatin (100,000U per 5 mL) suspension50 mL prednisolone at 15mg per 5ml solution50 mL distilled waterDisp: #300 mL (15 day supply)Sig: Swish thoroughly, gargle, and spit one teaspoonful (5 mL) after meals and before bed. Shake well before using.Note to prescriber: May be swallowed if the pharynx or esophagus is involved, but prescriber should consider systemic dosing as well as precautions against alimentation while the pharynx and larynx are numb. Oral, pharyngeal, and/or laryngeal numbness increases risk for aspiration, and therefore I tell my patients to use this after eating or drinking, not before, which may seem counterintuitive. Magic Mouthwash Recipe 2 (also called "Xyloxadryl," "BMX," or “Radiotherapy Mixture”)Rx:70 mL viscous lidocaine 2%70 mL Maalox (do not substitute Kaopectate)70 mL diphenhydramine (Benadryl) (of the elixir, which is 12.5 mg per 5 mL)Disp: 210 ml (10 day supply)Sig: Swish thoroughly, gargle, and spit one teaspoonful (5 mL) after meals and before bed. Shake well before using. Note to prescriber: May be swallowed if the pharynx or esophagus is involved, but prescriber should consider systemic dosing as well as precautions against alimentation while the pharynx and larynx are numb. Oral, pharyngeal, and/or laryngeal numbness increases risk for aspiration, and therefore I tell my patients to use this after eating or drinking, not before, which may seem counterintuitive. Magic Mouthwash Recipe 3Rx:38 mL viscous lidocaine 2%75 mL Maalox (do not substitute Kaopectate)38 mL diphenhydramine (Benadryl) 12.5 mg per 5 ml elixir50 mL sucralfate (Carafate) at 1 gm per 10 mlDisp: #200 mL (10 day supply)Sig: Swish thoroughly, gargle, and spit one teaspoonful (5 mL) after meals and before bed. Shake well before using.Note to prescriber: May be swallowed if the pharynx or esophagus is involved, but prescriber should consider systemic dosing as well as precautions against alimentation while the pharynx and larynx are numb. Oral, pharyngeal, and/or laryngeal numbness increases risk for aspiration, and therefore I tell my patients to use this after eating or drinking, not before, which may seem counterintuitive. Magic Mouthwash Recipe
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