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Author: Admin | 2025-04-28
If you sometimes struggle with premature ejaculation, you may have heard from a healthcare provider (or even just the internet): one of the best ways to treat PE may be a type of prescription you don’t associate with sexual medicine. The medication in question? Antidepressants.While it sounds a little suspicious, there’s plenty of randomized clinical trial research, placebo-controlled study data and other research out there showing that Prozac can be an effective treatment when you’re finishing too quickly. If you want to know how it works, you could wade through DOI studies, PubMed and Google Scholar articles and a whole lot of full-text reports from academic journals trying to figure out if studies should be double blind — or you could just let us walk you through them.Below, we’ve covered how ProzacⓇ works, how they can address premature ejaculation (PE) and what to know about taking them safely. We’ve also thrown in some alternatives, in case your quest to delay ejaculation isn’t ready for pharmacologic options quite yet.What Is Prozac (Fluoxetine)?Prozac is the brand name of fluoxetine — a selective serotonin reuptake inhibitor, or SSRI.SSRIs like Prozac increase the amount of serotonin available in your brain, so that it has a constant supply for helping to impact your mood and managing happiness, anxiety and other feelings.Prozac is currently only approved by the Food and Drug Administration for: Major depressive disorderObsessive compulsive disorder (OCD)Panic disorderBulimia nervosaIt’s often used off-label for other purposes (more on that in a moment).When used as directed, it’s a safe and effective medication with manageable adverse effects — and can give you more than one kind of relief.Does Prozac Work to Treat Premature Ejaculation?Here’s the low-down: Prozac wasn’t designed for treating premature ejaculation, but put simply, scientific research shows that fluoxetine, the active ingredient in Prozac, is effective as a treatment for PE. Specifically, some research suggests it’s effective at slowing down your orgasm and ejaculation processes. A 2009 study in the Journal of Sex Medicine (AKA J Sex Med) looked at 130 men using 20mg fluoxetine for PE. Although many of the men stopped using fluoxetine
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