Drugs for urinary urgency

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Author: Admin | 2025-04-28

Explore a selection of our essential drug information below, or:DescriptionA medication used to treat urinary and bladder symptoms.DescriptionA medication used to treat urinary and bladder symptoms.DrugBank IDDB01591TypeSmall MoleculeUS ApprovedYESOther ApprovedYESTherapeutic CategoriesAnticholinergic Agents Muscarinic Antagonists Mechanism of ActionMuscarinic acetylcholine receptor M3AntagonistSummarySolifenacin is a muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.Brand NamesVesicareGeneric NameSolifenacinDrugBank Accession NumberDB01591BackgroundSolifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.3 It has a long duration of action as it is usually taken once daily.3Solifenacin was granted FDA approval on 19 November 2004.3TypeSmall MoleculeGroupsApprovedStructureWeightAverage: 362.473 Monoisotopic: 362.199428085 Chemical FormulaC23H26N2O2SynonymsSolifenacinSolifenacinaExternal IDs YM-67905YM-905IndicationSolifenacin tablets are indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.3Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.Associated ConditionsContraindications & Blackbox WarningsPrevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical APIPharmacodynamicsSolifenacin antagonizes the M2 and M3 muscarinic receptors in the bladder to treat an overactive bladder.3,2 It has a long duration of action as it is usually taken once daily.3 Patients taking solifenacin should be aware of the risks of angioedema and anaphylaxis.3Mechanism of actionSolifenacin is a competitive muscarinic receptor antagonist.3 It has the highest affinity for M3, M1, and M2 muscarinic receptors.1 80% of the muscarinic

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