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Author: Admin | 2025-04-28
Increase the risk of side effects from Cialis†certain antifungal drugs• itraconazole (Sporanox, Tolsura)• levoketoconazole (Recorlev)• ketoconazole• voriconazole (Vfend)can increase the risk of side effects from Cialis†certain antibiotic drugs• clarithromycin• erythromycin (E. E.S., EryPed, Ery-Tab, others)• rifampin (Rifadin, Rimactane)can increase the risk of side effects from Cialis†certain antiseizure drugs• carbamazepine (Carbatrol, Epitol, Tegretol, others)• phenobarbital• phenytoin (Dilantin, Phenytek)can make Cialis less effective than usual * For details about this interaction, see “When to avoid Cialis” above.† To learn about possible side effects of Cialis, see this article. Here’s a closer look at certain drug interactions of Cialis.PDE5 inhibitorsPhosphodiesterase 5 (PDE5) inhibitors are medications used to treat conditions such as pulmonary arterial hypertension and erectile dysfunction.Interaction result. Taking a PDE5 inhibitor with Cialis can increase the risk of low blood pressure.Interaction explained. Cialis belongs to a class of drugs called PDE5 inhibitors. Medications in this class, including Cialis, can lower blood pressure. Taking Cialis with other drugs in the same drug class can increase the risk of low blood pressure further.Examples of PDE5 inhibitors. PDE5 inhibitors that may interact with Cialis include the following:avanafil (Stendra)vardenafil (Staxyn)sildenafil (Viagra, Revatio)other forms of tadalafil (Adcirca, Alyq)Steps you or your doctor may take. Due to this risk, doctors typically will not prescribe Cialis in combination with other PDE5 inhibitors. Before taking Cialis, it’s important to tell your doctor if you’re already taking a PDE5 inhibitor. They’ll likely prescribe a treatment other than Cialis for your condition.Certain antibiotic drugsAntibiotic drugs are used to treat infections caused by bacteria.Interaction result. Taking Cialis with certain antibiotics can increase the risk of side effects of Cialis. (To learn more about the side effects of Cialis, see this article.)Interaction explained. Certain antibiotics can prevent your body from breaking down Cialis. This can result in a higher level of the drug in your body than usual. A high level of the drug in your system could increase risk of side effects from Cialis.Examples of antibiotic drugs. Below are a few antibiotics that may interact with Cialis:clarithromycinerythromycin (E.E.S., EryPed, Ery-Tab, others)rifampin (Rifadin, Rimactane)Steps you or your doctor may take. If you’re taking an antibiotic, talk with your doctor before starting Cialis treatment. They can advise you on whether it’s safe for you to take Cialis with these medications.Certain antiseizure drugsAntiseizure drugs are used to treat seizure disorders such as epilepsy.Interaction result. Taking Cialis with certain antiseizure drugs can make Cialis less effective than
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