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Author: Admin | 2025-04-28
Low-risk, reliable, and sensible drug.An abundance of data shows mifepristone is extremely safeMifepristone works by blocking the progesterone hormone. During pregnancy, this hormone helps keep the lining of the uterus intact; without it, a pregnancy cannot go on.But mifepristone isn’t enough to end a pregnancy: If the uterus isn’t emptied after an abortion, there’s a high risk of bleeding or infection that could be life-threatening to the patient. That’s why, 24 to 48 hours after taking mifepristone, people getting medical abortions then take misoprostol. That drug relaxes the opening to the uterus and helps the uterus contract and empty itself.When mifepristone was first FDA-approved for abortions in 2000, it had already been in use in France since 1988. Back then, there was already a fair amount of data suggesting the drug, in combination with a medication like misoprostol, effectively ended pregnancies in 95 percent of the people who took it for that purpose. Additionally, its side effects were mild and included nausea and vomiting, dizziness, weakness, abdominal pain, and headache. Still, at the time of the drug’s US approval, the FDA placed several restrictions on its distribution, among them a requirement that doctors prescribing it report any hospitalization, transfusion, or other serious events to the agency. Many FDA-approved drugs come with some safety risks. We can’t expect any medicine to have no potential side effects; what’s important is that we understand them. In mifepristone’s case, the high level of scrutiny means that over the last 23 years, “huge amounts of
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