titration from liothyronine to levothyroxine. Further work is There is no defined conversion factor, and conversion of patients from
Liothyronine (T3) is the active thyroid hormone and the majority is produced by peripheral conversion of levothyroxine (T4).
A conversion factor of mcg (levothyroxine) to 5-10mcg (liothyronine) is reasonable approach. For example, the dose of levothyroxine can be reduced by 25mcg daily at the time of initiation of liothyronine (a dose of 5mcg administered in the morning).
Dose equivalence and conversion for liothyronine sodium 20–25 micrograms of liothyronine sodium is equivalent to approximately 100 micrograms of levothyroxine
however UK guidance states (1) there is no defined conversion factor, and conversion of patients from liothyronine to levothyroxine monotherapy will require a reduction in the dose of liothyronine and an increase in levothyroxine. A reduction of dose of liothyronine by 10 micrograms will probably require an increase in dose of levothyroxine of
A conversion factor of mcg (levothyroxine) to 5-10mcg (liothyronine) is reasonable approach. For example, the dose of levothyroxine can be reduced by 25mcg daily at the time of initiation of liothyronine (a dose of 5mcg administered in the morning).
Conversion Chart: Natural Desiccated Thyroid, Levothyroxine, and Liothyronine/T3 The following is a general conversion chart, showing the dosage equivalents
A conversion factor of mcg (levothyroxine) to 5-10mcg (liothyronine) is reasonable approach. For example, the dose of levothyroxine can be reduced by 25mcg daily at the time of initiation of liothyronine (a dose of 5mcg administered in the morning).
by J Jonklaas 2024 Cited by 238thyroxine to triiodothyronine conversion Combined therapy with levothyroxine and liothyronine in two ratios, compared with levothyroxine
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