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Phenytoin and carbamazepine can cause a brownish-grey pigmentation of the skin. 10% of patients develop pigmentation of the face and neck resembling melasma (
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The blue-grey discolouration of the skin appears mainly (but not only) on places that are exposed to direct sunlight (this means it affects mainly the face and hands). It is caused by accumulation of amiodarone and its metabolites in the skin. The blue-grey discolouration is not completely reversible after discontinuation of the drug. Case report
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Amiodarone may also cause slate-grey pigmentation of the skin. This is Ensure they have an adequate supply of medication. Attend appointments.
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Skin discoloration: Amiodarone can cause a disfiguring (and possibly permanent) blue-grey discoloration of the skin, generally in areas of sun exposure. Sun
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What Are the Long-Term Side Effects of Amiodarone? Halo vision, caused by deposits formed on the cornea. Blue-grey skin discolorations
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Psychotropic drugs most often cause changes in skin pigmentation in areas of the skin which are exposed to the sun. Often a blue-grey pigmentation will develop
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Skin side effects are common, they usually occur as photosensitivity, more rarely as a slate-grey discoloration of the skin. Amiodarone induced slate-grey
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by AM Farhat-Sabet 2024Typical blue–grey skin discoloration seen in amiodarone-induced ceruloderma. Figure 1. Typical blue–grey skin discoloration seen in amiodarone
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What are the clinical features of drug-induced pigmentation? Phenytoin and carbamazepine can cause a brownish-grey pigmentation of the skin. 10% of patients
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On the plus side, no liver spots when you are older, less wrinkles too 'cause pink skin in the sunlight often takes a nose dive.