Fluoroquinolones, including ciprofloxacin tablets have been associated with an increased risk of seizures (convulsions), increased intracranial pressure (pscudotumor cerebri), dizziness, and tremors. Ciprofloxacin tablets, like other fluoroquinolones, is known to trigger seizures or lower the seizure threshold.
A systematic review of 143 articles on seizures associated with 25 different antibiotics, including ciprofloxacin. Ciprofloxacin was reported to increase the risk of seizures in patients with renal dysfunction, mental disorders, prior seizures, or coadministered theophylline.
Ibuprofen potentially increases the risk of seizures when given with Ciprofloxacin. Melatonin. Ciprofloxacin is predicted to increase the exposure to
Ciprofloxacin and imipenem may lower seizure threshold and cause seizures in patients without a prior history of epilepsy.
Co-administration of probenecid and ciprofloxacin increases ciprofloxacin serum concentrations. sore throat; seizures; severe or persistent dizziness or
valproate 10 mg/kg Ciprofloxacin 25 mg/kg Ciprofloxacin Bupropion seizure proportion among new-onset generalized seizures drug related seizures presenting
Ciprofloxacin should be use with caution in patients with CNS disorders which may be predisposed to seizure. If seizures occur ciprofloxacin.
Ciprofloxacin has been shown to cause photosensitivity reactions. Patients taking ciprofloxacin should be advised to avoid direct exposure to either extensive sunlight or UV irradiation during treatment (see section 4.8). Seizures. Ciprofloxacin like other quinolones are known to trigger seizures or lower the seizure threshold.
Seizures: There have been occasional reports of seizures occurring with clomipramine. quinolone antibiotics (e.g, ciprofloxacin, levofloxacin, ofloxacin)
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