Acyclovir renal toxicity
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Background and Objective: Acyclovir is primarily cleared by the kidneys. Therefore, renal adjusted dosing is required for patients with renal impairment to prevent drug toxicity.
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by KC Zachary Cited by 5INDICATIONS FOR ACYCLOVIR DOSE ADJUSTMENTS Reduced renal function Obesity Acyclovir resistance TOXICITY Acute renal failure
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by MJ Desrumaux 2024Other renal side effects of acyclovir are acute tubular toxicity and interstitial nephritis. Additionally, acyclovir can induce encephalopathy.
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by KC Zachary Cited by 5INDICATIONS FOR ACYCLOVIR DOSE ADJUSTMENTS Reduced renal function Obesity Acyclovir resistance TOXICITY Acute renal failure
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Renal Toxicity: Acyclovir precipitates in the renal tubules, leading to crystallization, which can cause kidney damage. Neurological Symptoms: High doses
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In general, acyclovir is a well-tolerated medication. The adverse effects most often associated with acyclovir are renal dysfunction, related to crystalluria, phlebitis, and neutropenia. Adequate hydration is recommended during acyclovir therapy in order to prevent renal toxicity.
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Renal Toxicity: Acyclovir precipitates in the renal tubules, leading to crystallization, which can cause kidney damage. Neurological Symptoms: High doses may
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Renal Toxicity: Acyclovir precipitates in the renal tubules, leading to crystallization, which can cause kidney damage. Neurological Symptoms: High doses may
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Acute renal failure with acyclovir treatment in a child with leukemia. The significant role of acyclovir aldehyde in the direct renal toxicity may be
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