Quinoline drugs

☑️@quinoline_drugs · 2110 subscribers · Content 18+ 🔞
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Actual: Quinoline and 4-quinolone (Fig. 1) moieties were used as a scaffold for drug development for more than two centuries (Heeb et al. 2024). The most successful drug based on quinoline scaffold is chloroquine (Fig. 1), which was specifically developed as antimalarial agent. Until today, numerous quinoline-based compounds and drugs were developed as
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demonstrated that quinoline drugs have antibacterial activity, suggesting that these drugs may be an quinoline drugs or with CMCM (used for drug free).

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Similar to ARTs, the design and synthesis of quinoline drugs, which are characterized by a quinoline ring, has been researched for application as antimalarial drugs. Quinolines exert their antimalarial effects during the blood or liver stages of the life cycle of the parasite ( 140 ), but different drugs have different mechanisms ( 141, 142 ).

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Several anti-malarial drugs contain quinoline substituents. These include quinine, chloroquine, amodiaquine, and primaquine. Quinoline is used as a solvent

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Quinolines are neurotoxic drugs that have been widely used in malaria treatment and prevention, particularly in military settings. Poisoning by quinoline drugs, including by the previously commonly used drugs quinacrine, chloroquine, and mefloquine, can cause a

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by P Yadav 2024 Cited by 150The antimalarial drugs bearing quinoline rings are quinine, quinidine, chloroquine, mefloquine, amodiaquine, primaquine, bulaquine as quinoline derivatives [4]

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Quinoline is a heterocyclic organic compound. The chemical name of quinoline is alpha, beta benzopyridine. The molecular formula for quinoline is C 9 H 7 N. In the quinoline molecular formula, then C represents the carbon, H represents the hydrogen and the numbers written in subscript represent the number of respective elements.

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Antibiotics, Macrolide, Miscellaneous, Prodrugs, Antimalarials, Quinolines, Biguanides and dihydro triazines, Miscellaneous drugs

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Antibiotics, Macrolide, Miscellaneous, Prodrugs, Antimalarials, Quinolines, Biguanides and dihydro triazines, Miscellaneous drugs

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Quinoline and its derivatives comprise an important group of heterocyclic compounds that exhibits a wide range of pharmacological properties such as antibacterial, antiviral, anticancer, antiparasitic, anti-Alzheimer and anticholesterol. The quinoline nucleus is found in the structure of many drugs

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