Drugs interfering with the cytochrome P450 (CYP450) enzyme system should be avoided with bedaquiline. This list is not exhaustive.
Drugs that induce CYP450 enzymes taking metronidazole with phenytoin, phenobarbital, or other drug that stimulate CYP450 enzymes can cause metronidazole to leave the body too quickly; Please note that this list may not be complete, and other interactions with drugs not listed here may occur. Metronidazole and Clindamycin
Berberine Drug Interactions Drugs metabolized by CYP450: CYP450 is an abundant enzyme in the liver responsible for metabolizing many
Precautions The effectiveness of this drug is dependent upon activation to an active metabolite via the CYP450 system, principally CYP450 2C19.
The primary form of drug metabolism for most statins occurs through CYP450 enzymes. The most prevalent CYP450 enzyme subcategories for statin
Concomitant use or discontinuation of CYP450 isoenzymes including CYP450 3A4 inducers, CYP450 3A4 inhibitors, or CYP450 2D6 inhibitors are complex; concomitant use requires careful consideration of the effects on the parent drug, tramadol, and the active metabolite, M1.
by M Deodhar 2024 Cited by 49The drug is extensively metabolized by several cytochrome P450 (CYP450) enzymes and subjected to a myriad of CYP450-mediated drug interactions.
Lorazepam is metabolized differently from these common benzodiazepines, SSRIs, and SNRIs. Metabolic Pathway. Medication, CYP450 2C19, CYP450 2D6, CYP450 3A4
drug's potential to inhibit the following specific CYP450 enzymes. CYP1A2 A list of reversible inhibitors includes α-naphthoflavone, sertraline
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