Leucovorin and methotrexate

a combination of vitamin A and a single dose of methotrexate and a combination of leucovorin and methotrexate, respectively. The last group

Leucovorin for methotrexate and 5-FU for methotrexate: rescue theapy for 5-FU a final cinfirmation 【Reference and figure】

Leucovorin rescue4 is required in some methotrexate regimens. Methotrexate dose: ▫ 500 mg/m2 requires leucovorin rescue. ▫ mg/m2 may

Example of a nomogram for pharmacokinetically guided leucovorin rescue after high-dose methotrexate(MTX) administration HDMTX = high-dose methotrexate;

Leucovorin rescue4 is required in some methotrexate regimens. Methotrexate dose: ▫ 500 mg/m2 requires leucovorin rescue. ▫ mg/m2 may

Leucovorin Leuprorelin Levamisole Levetiracetam Levocetirizine Levodopa Methotrexate Methoxsalen Methylcellulose Methylcobalamin

Methotrexate in high doses, followed by leucovorin rescue, is used as a part of the treatment of patients with non-metastatic osteosarcoma. The original rationale for high dose methotrexate therapy was based on the concept of selective rescue of normal tissues by leucovorin. More

Methotrexate must be given in a hospital where rapid reporting of methotrexate levels is available. Plasma methotrexate levels are performed routinely each morning after starting the methotrexate infusion. At 24 hours, leucovorin rescue begins according to the protocol. A dose of leucovorin 25 mg q6h is used initially.

Leucovorin calcium for injection dosages are not adjusted for toxicity. Leucovorin Rescue After High-Dose Methotrexate Therapy. The recommendations for leucovorin rescue are based on a methotrexate dose of grams/m 2 administered by intravenous infusion over 4 hours (see methotrexate package insert for full prescribing information).