Citrate lock

One newly developed locking solution has reduced the ethanol concentration in the locking solution to 20% in combination with 0.01% glyceryl trinitrate and 7% citrate. This lock showed promising results in eradicating biofilm in an in vitro test .

These antimicrobial lock solutions could be divided into antibiotic (e.g. vancomycin) and non‐antibiotic (e.g. citrate) solutions. Antimicrobial lock solutions should fill the catheter lumen and then be locked in the catheter during in‐between HD sessions with or without heparin.

by AN Mattingly 2024Sodium citrate is an alternative to heparin for use as a catheter lock solution.15 Sodium citrate is an anticoagulant that works by binding to calcium, a

by DA Pierce 2024 Cited by 28trisodium citrate (also known as sodium citrate or citrate) has recently been shown to be an efficacious alternative to heparin as a locking solution.

Nori et al. confirmed that gentamicin (4 mg/mL)/citrate and minocycline/EDTA lock solutions were superior to heparin lock alone in the prevention of CRBSI, and the curative effect was

Whether citrate lock is more effective than saline solution or heparin lock in intensive care unit (ICU) settings and whether it is associated with a lower incidence of CRBSI remain unclear . We hypothesized that the risk of dialysis catheter infection would be lower with the use of sodium citrate locks in the ICU. This study aimed to compare

Antimicrobial-containing citrate lock solutions are more effective than heparin lock solutions for the prevention of catheter-related bloodstream infections (CRBSIs), say researchers.

Further loss of lock solution due to gravity should be considered if lock solutions (e.g. citrate 30 or 46.7%) with a density higher than blood are used [12] [13] [14]. In this case, the mentioned

Citrate at 4 % has proven effective against low potential of complications and are broadly accepted standard amongst citrate lock solution at present. read more hide Study by Solomon et al. on lock solutions in dialysis (2025) The