Drugs that lower uric acid

These flares early in uric-acid-lowering treatment (such as allopurinol) are not a reason to stop the uric-acid-lowering medication. For the

The drug allopurinol is the most commonly used uric-acid-lowering medication. It restricts the breakdown of purines and so reduces uric acid

Medications that improve uric acid removal. Drugs such as probenecid (Probalan) lower uric acid in a different way from allopurinol and

Medications that improve uric acid removal. Drugs such as probenecid (Probalan) lower uric acid in a different way from allopurinol and

When starting a uric acid-lowering drug, flares of gout are common because any change in uric acid (up or down) can trigger an attack. For this reason, an anti-inflammatory drug such as colchicine is recommended for at least the first few months of uric acid-lowering treatment. Allopurinol is the first-line uric acid lowering drug.

The PharmGKB Uric Acid-Lowering Drugs Pathway, PD covers drugs that either inhibit formation of uric acid or act directly upon uric acid to increase secretion.

Medications that improve uric acid removal. Drugs such as probenecid (Probalan) lower uric acid in a different way from allopurinol and

Medications that improve uric acid removal. Drugs such as probenecid (Probalan) lower uric acid in a different way from allopurinol and

Medications that improve uric acid removal. Drugs such as probenecid (Probalan) lower uric acid in a different way from allopurinol and