♢ Methadone accumulates with repeated dosing. Chronic dosing Conversion from IV to PO: Example Morphine 10 mg IV = 30 mg PO (multiple by
Additionally, IV to oral (PO) conversion of morphine was 3:1, IV to PO hydromorphone was 5:1, and PO morphine to PO oxycodone was 1:1.5. (Franck et al
Furosemide. IV to PO conversion is ~1 mg IV to 2 mg PO. 12. Bioavailability is ~50% for furosemide tablets and oral solution. 12. Intravenous to oral conversion
Table 2. Conversion of Opioid Analgesics to Fentanyl Transdermal ; Morphine PO. . ; Morphine IV/IM. . ; Oxycodone PO. 30-
Furosemide. IV to PO conversion is ~1 mg IV to 2 mg PO. 12. Bioavailability is ~50% for furosemide tablets and oral solution. 12. Intravenous to oral conversion
1.5 mg IV Hydromorphone = 100 mcg IV/SC Fentanyl = 20 mg PO Oxycodone = 10 mg IV Morphine. Conversion from IV to PO: Example Morphine 10 mg IV = 30 mg PO
(IV/PO)1,2,70,71. (Use adjusted BW for obesity). IV: 6 mg/kg IV q12h x 2, then 4 mg/kg IV q12h. PO: 400 mg PO q12h x 2, then 200 mg PO q12h. IV→PO conversion
1.5 mg IV Hydromorphone = 100 mcg IV/SC Fentanyl = 20 mg PO Oxycodone = 10 mg IV Morphine. Conversion from IV to PO oral) was considered approximately.
1) Using the IV morphine:PO morphine conversion ratio, convert to PO morphine: X = 60 mg PO morphine 20 mg IV morphine = 10 mg IV morphine X mg PO morphine 30 mg PO morphine 2) Using the PO morphine:PO oxycodone conversion ratio, convert to PO oxycodone: X = 40 mg PO oxycodone 60 mg PO morphine = 30 mg PO morphine
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Regards, Jack