Fosphenytoin vs phenytoin

Phenytoin vs Fosphenytoin. The efficacy of phenytoin and fosphenytoin for time to seizure cessation are comparable, however there are theoretical reasons why fosphenytoin might be preferred: Phenytoin and fosphenytoin have sodium channel blockade effects, which is similar to the mechanism of action of certain toxidromes such as TCA and cocaine

the plasma fosphenytoin, total phenytoin, and unbound phenytoin concentration-time patients vs 11% of IM placebo-treated patients at

They reported that levetiracetam was not superior to phenytoin. Comparing levetiracetam vs. fosphenytoin vs. valproate groups – no

vs 0.61 ± 0.02 L/kg) in patients with Fosphenytoin and phenytoin in patients with status epilepticus: improved tolerability versus increased costs.

Fosphenytoin is a water-soluble prodrug of phenytoin. After IV administration, much of the fosphenytoin is metabolized to phenytoin within 15

Fosphenytoin, also known as fosphenytoin sodium, and sold under the brand name Cerebyx among others, is a water-soluble phenytoin prodrug that is administered intravenously to deliver phenytoin, potentially more safely than intravenous phenytoin. It is used in the acute treatment of convulsive status epilepticus. Fosphenytoin was developed in

Comparing Fosphenytoin vs Phenytoin ; Be the first to share your experience with this drug. Phenytoin has an average rating of 7.5 out of 10 from a total of 112

They reported that levetiracetam was not superior to phenytoin. Comparing levetiracetam vs. fosphenytoin vs. valproate groups – no

Because its molecular weight is different than that of phenytoin, one milligram of fosphenytoin does not equal one milligram of phenytoin. To avoid confusion, fosphenytoin doses are reported as mgPE (milligrams of phenytoin equivalents). Using mgPE, no adjustment is needed when converting between phenytoin and fosphenytoin. Oral vs. IV