Drugs that cause neutropenia

Infections are the most common cause of neutropenia in adults, followed by drug-induced neutropenias. Andres E, Federici L, Weitten T, et al. Recognition and management of drug-induced blood cytopenias: the example of drug-induced acute neutropenia and agranulocytosis.

The most common drugs associated with severe neutropenia are antithyroid medications, ticlopidine, clozapine, sulfasalazine, trimethoprim-sulfamethoxazole, and dipyrone. 14 The mAb anti-CD20 (rituximab) also causes late-onset neutropenia. 15 If a potential causative agent is identifiable, drug-induced neutropenia is sometimes reversible at

Drug- induced neutropenia is an acquired neutropenia that is potentially 13 Table 48-1 lists drugs that have been reported to cause agranulocytosis

The most common drugs associated with severe neutropenia are antithyroid medications, ticlopidine, clozapine, sulfasalazine, trimethoprim-sulfamethoxazole, and dipyrone. 14 The mAb anti-CD20 (rituximab) also causes late-onset neutropenia. 15 If a potential causative agent is identifiable, drug-induced neutropenia is sometimes reversible at

Many other drugs can cause neutropenia less commonly and reviewing the and in whom benign ethnic neutropenia, drug- induced neutropenia and other

Others causes of acquired neutropenia, such as primary immune mechanisms, chemotherapy, and infections, as well as congenital neutropenia in children are discussed separately. (See Immune neutropenia and Infectious causes of neutropenia and Congenital neutropenia and Overview of neutropenic fever syndromes .)

FDA Drug Safety Communication: FDA modifies monitoring for neutropenia neutrophils in the blood, in some cases causing severe neutropenia.

Drugs causing neutropenia. Although relatively rare, drug therapy may cause an acquired neutropenia in some people. The drugs most likely to be associated

Drugs given to treat these infections may also cause neutropenia. (See Drug-induced neutropenia and agranulocytosis .) This review will discuss the neutropenias that can occur during bacterial, viral, parasitic, or rickettsial infections. Approaches to determining the cause of unexplained neutropenia in children and adults are presented