Warfarin (Maforan, Orfarin). ชื่อสามัญ. (Generic name). Warfarin Tablet 2 mg Erythromycin, Metronidazole, Fluconazole, Itraconazole. Ketoconazole
azithromycin; Azole antifungals: fluconazole, voriconazole; Cardiac drugs Warfarin: Point-of-Care INR Monitoring of Warfarin Therapy. References
Fluconazole/warfarin. Increase in INR: case report. Erschienen in: Reactions Weekly
For example, when warfarin is given concomitantly with fluconazole, a potent inhibitor of CYP2C9, fluconazole will inhibit warfarin's
warfarin dose if needed. fluconazole. fluconazole will increase the level or effect of warfarin by affecting hepatic enzyme CYP2C9/10 metabolism. Modify
Pomegranate juice increases the INR in response to warfarin. Warfarin has the following interaction information: Fluconazole increases the anticoagulant effect of
by EV Hersh Cited by 2avoidance of fluconazole is recommended in patients taking warfarin fluconazole and metronidazole can inhibit warfarin's metabolism and lead to
Warfarin's primary metabolic pathway involves the cytochrome P450 2C9 isoform, and fluconazole is a strong inhibitor of this enzyme. Avoidance of fluconazole in patients on warfarin is advisable unless the dose of warfarin is empirically reduced and the INR is closely monitored.
Fluconazole, ↑. Hold warfarin x1 for single dose. Expect % warfarin dose reduction for extended course. ; Fluoroquinolones, ↑. Not always clinically
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