In such cases, the metabolism remains constant despite increases in the dose of the drug. This is referred to as zero-order kinetics. Metabolic Enzymes. The
Metabolic Changes: Atypical antipsychotic drugs have been associated with metabolic changes that may increase cardiovascular/cerebrovascular
metabolism by stimulating fat metabolism, and increases endurance. However, at higher doses, the drug tends to. promote aggressiveness
Hepatic metabolism of the statins increases risk of drug interactions with other medications that share the same hepatic metabolic pathways. For simvastatin
Metabolic Changes: Atypical antipsychotic drugs have been associated with metabolic changes that may increase cardiovascular/cerebrovascular
Metabolic Changes: Atypical antipsychotic drugs have been associated with metabolic changes that may increase cardiovascular/cerebrovascular
metabolism by enzyme inhibition or increased drug metabolism contribute to differing rates of excretion and impact dosing of medications.
Metabolism: CCBs are extensively hepatically metabolized. In repeated doses or overdose, the hepatic enzymes responsible for metabolism become saturated and reduce first-pass effects, increasing absorption of the active drug. Modified release formulations and saturation of metabolism of these drugs increase the half-life of various CCBs.
Metabolic Changes: Atypical antipsychotic drugs have been associated with metabolic changes that may increase cardiovascular/cerebrovascular
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