by R MacLaren 2024 Cited by 256Famotidine was the most common H2RA prescribed, and 12.7% of patients receiving H2RAs received high-dose administration. Pantoprazole was the
The relative efficacy and drug-related adverse events of PPIs and H2RAs remain unclear. The PPI group had a significantly higher 90-day mortality than the H2RA group (relative risk: 1.28; P
H2 Antagonists. (H2RA). Proton Pump. Inhibitors (PPIs). equivalent doses: H2RAs If coadministration is unavoidable, ↑ to atazanavir 400/100 mg and do not
Acid Suppression with PPIs versus H2RAs. The acid suppressing effects of CI omeprazole and H2RAs have been examined in comparative trials.
drugs, antiarrhythmic drugs, beta Whereas a baseline analysis addresses mechanisms not anchored on active presence of H2RA drug
by J Yu 2024Histamine H2-receptor antagonist (H2RA) is a commonly prescribed drug, and ranitidine, a representative drug of H2RA, is often known to cause an immediate
by R MacLaren 2024 Cited by 256Famotidine was the most common H2RA prescribed, and 12.7% of patients receiving H2RAs received high-dose administration. Pantoprazole was the
H2 receptor antagonists (H2RAs) reduce stomach acid and are used to treat indigestion, acid reflux, and stomach ulcers. H2RAs available in the UK include
Finally, the recent trend of developing OTC drugs as combination formulations of an antacid and an H2RA is a concern because these drugs will increase the risk of DDIs by dual mechanisms, i.e. a gastric pH-dependent mechanism by H2RAs and a cation-mediated chelation mechanism by antacids.
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