Abuse of gabapentinoids

Synonyms were combined. (abuse: misuse, opioids: opioid, drug abuse: drug misuse, addiction: dependence, gabapentinoids: gabapentinoid), after

gabapentin and pregabalin, collectively known as gabapentinoids. Gabapentinoid abuse in order to potentiate the effect of methadone: a survey

Background: A 2024 systematic review (SR) identified 59 studies examining gabapentinoid (pregabalin and gabapentin) misuse/abuse. Evidence of gabapentinoid misuse/abuse has since grown substantially. Objective: Update previous SR and describe new insights regarding gabapentinoid abuse.

The abuse of gabapentinoids (i.e, pregabalin and gabapentin [GBP]), in particular, has been growing, and in 2024, gabapentinoids were one of the most commonly abused prescription medications

The gabapentinoids, pregabalin and gabapentin are abused and misused particularly by those with a history of drug abuse. Those with an opioid use disorder seem to be more prone to abuse gabapentinoids than patients with other substance use disorders.

Reports of gabapentinoid abuse alone, and with opioids, have Gabapentinoid products include gabapentin, which is marketed under the name

Background/aims: There is emerging evidence of gabapentin and pregabalin (gabapentinoid) abuse, particularly in the substance misuse population, and some suggestion of gabapentinoids being abused alongside methadone.

Conclusion Evidence suggests gabapentinoids possess potential for abuse, particularly in individuals with a history of opioid abuse, and reports of such abuse

Conclusion Evidence suggests gabapentinoids possess potential for abuse, particularly in individuals with a history of opioid abuse, and reports of such abuse