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Interaction between CBD oil and levothyroxine: As mentioned earlier, both CBD oil and levothyroxine can help with hypothyroidism. If spaced out between the use of CBD oil and levothyroxine properly, there may be minimal or no effect at all.
As such, there could be negative interactions between levothyroxine and CBD oil because CBD could slow the rate at which levothyroxine is metabolised. This
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Levothyroxine can inhibit cytochrome p450 enzyme CYP3A4, which metabolizes CBD in the body. A small study found that children taking CBD who were also taking levothyroxine had higher blood levels of CBD compared to those taking the same dose of CBD but without levothyroxine.
These include known side effects of CBD, but also unintended interactions a thyroid medication, levothyroxine; several medications for
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