Interaction amlodipine and simvastatin

Istin (amlodipine) Co-administration of multiple doses of 10mg of amlodipine with 80mg simvastatin resulted in a 77% increase in exposure to simvastatin compared to simvastatin alone. Limit the dose of simvastatin to 20mg daily in patients on amlodipine. In clinical interaction studies, amlodipine did not affect the pharmacokinetics

by YT Zhou 2024 Cited by 73lacidipine–simvastatin, amlodipine–simvastatin, benidipine-simvastatin, azelnidipine– amlodipine–simvastatin interaction information. Since a dose reduction

the drug-drug interaction between amlodipine and simvastatin except simvastatin or patients receiving simvastatin without amlodipine

reported, but none with a simvastatin-amlodipine interaction. [16, 17] gerous interactions of some statins (simvastatin) with drugs.

Simvastatin จัดเป็นยาในกลุ่ม statin Interaction between amlodipine and simvastatin in patients with hypercholesterolemia and hypertension.

reported, but none with a simvastatin-amlodipine interaction. [16, 17] gerous interactions of some statins (simvastatin) with drugs.

by CG Park 2024 Cited by 34Non-concurrent dosing attenuates the pharmacokinetic interaction between amlodipine and simvastatin Interaction between amlodipine and simvastatin in patients

amlodipine. Rationale: Drug‐drug interaction of simvastatin with amlodipine leads to an estimated 30% increase in the plasma concentration of simvastatin

However, there is a drug interaction between simvastatin and amlodipine. Amlodipine can increase the concentration of simvastatin which