Supratherapeutic inr meaning

Medline Abstracts for References of 'Management of warfarin-associated bleeding or supratherapeutic INR' mean INR was 10.4 at presentation.

If concomitant use of a drug that alters INR cannot be avoided, ↑ INR monitoring Step 3: Identify if sub-/supratherapeutic INR is a result of a permanent

This topic discusses risk factors for warfarin-associated bleeding and poor international normalized ratio (INR) control and presents an approach to the management of a patient with warfarin-associated bleeding or an INR above the therapeutic range (ie, a supratherapeutic INR).

For patients initiating prednisone therapy, preemptive warfarin dose reduction resulted in a non-significant reduction in supratherapeutic INR but increased

by P Tajai INR 2.0-3.0. - INR 2.5-3.5 (in a patient with a mechanical heart valve). 250 (93.6). 17 (6.4). Mean supratherapeutic INR (range)b. - INR 3.1-5.0. - INR 5.0.

INR/Clinical Scenario Bleeding Intervention Monitoring INR supratherapeutic but 4.5 No Lower or omit next dose Recheck INR the next day INR 4.5-10.0 No Lower or omit next dose Recheck INR the next day INR 10.0 No PO vitamin K 2.5-5mg (IV if unable to tolerate PO) Recheck INR the next day

Management of an elevated INR caused by warfarin therapy. A supratherapeutic INR is a significant risk factor for bleeding. General principles for preventing supratherapeutic INR involve careful monitoring and consideration of warfarin-drug interactions, including avoiding concomitant non-steroidal anti-inflammatory drugs, certain antibiotics and antiplatelet therapy except where clinical

Elderly patients are generally more sensitive to warfarin and need a lower mean daily dose. A supratherapeutic INR with no bleeding. Warfarin therapy

This single-centre retrospective chart review involved noncritical care inpatients with supratherapeutic INR (4.5 8.9) without evidence of bleeding. The primary outcomes were the change in INR 1 day after implementation of supratherapeutic INR management and the time to reach INR less than 3.0.