Metabolic Changes: Atypical antipsychotic drugs have been associated with metabolic changes that may increase cardiovascular/cerebrovascular
Metabolism: CCBs are extensively hepatically metabolized. In repeated doses or overdose, the hepatic enzymes responsible for metabolism become saturated and reduce first-pass effects, increasing absorption of the active drug. Modified release formulations and saturation of metabolism of these drugs increase the half-life of various CCBs.
cimetidine increases effects of buprenorphine buccal by decreasing metabolism. Avoid or Use Alternate Drug. buspirone. cimetidine will increase the level or effect of buspirone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. butorphanol. cimetidine increases effects of butorphanol by decreasing metabolism.
Metabolic Changes: Atypical antipsychotic drugs have been associated with metabolic changes that may increase cardiovascular/cerebrovascular
Although metabolism typically inactivates drugs, some drug metabolites are metabolism rate increases with drug concentration. In such cases, called
may lead to reduced metabolism, higher serum levels, and increased activity of Melatonin. Pharmacokinetics 1. Drug metabolism. Phentermine is
metabolism by enzyme inhibition or increased drug metabolism contribute to differing rates of excretion and impact dosing of medications.
Potential Drug Interactions ; Omeprazole. Increase. May inhibit of warfarin metabolism ; Metronidazole. Increase. Inhibits metabolism of S-isomer ; Nicardipine.
metabolism by stimulating fat metabolism, and increases endurance. However, at higher doses, the drug tends to. promote aggressiveness
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