Acyclovir renal toxicity
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Background and Objective: Acyclovir is primarily cleared by the kidneys. Therefore, renal adjusted dosing is required for patients with renal impairment to prevent drug toxicity.
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In general, acyclovir is a well-tolerated medication. The adverse effects most often associated with acyclovir are renal dysfunction, related to crystalluria, phlebitis, and neutropenia. Adequate hydration is recommended during acyclovir therapy in order to prevent renal toxicity.
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Many antiviral agents require dose adjustment in renal impairment. Acyclovir may cause renal impairment. Acyclovir may cause CNS toxicity. Foscarnet ↑ risk of
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Many antiviral agents require dose adjustment in renal impairment. Acyclovir may cause renal impairment. Acyclovir may cause CNS toxicity. Foscarnet ↑ risk of
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by KC Zachary Cited by 5Acyclovir resistance TOXICITY Acute renal failure Neurologic toxicity USE IN PREGNANCY IF THERE IS AN ACYCLOVIR SHORTAGE Overview of
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Renal Toxicity: Acyclovir precipitates in the renal tubules, leading to crystallization, which can cause kidney damage. Neurological Symptoms: High doses may
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by MJ Desrumaux 2024Other renal side effects of acyclovir are acute tubular toxicity and interstitial nephritis. Additionally, acyclovir can induce encephalopathy.
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